使用成对脉冲磁刺激(Paired pulse TMS)测量短间隔皮层内抑制（SICI）经常被用来研究运动皮质病理生理学。这些研究为许多疾病中抑制和兴奋平衡的改变提供了重要的支持证据。虽然到目前为止已经收集了大量关于导致SICI的神经网络和神经化学的可靠信息，但仍有许多问题没有得到解答。为了真正了解短间隔皮层内抑制（SICI）能告诉我们的运动皮质功能和功能障碍的信息，必须仔细考虑现有证据，并进行进一步的研究。在本次网络研讨会中，McMackin博士和Stagg教授将讨论短间隔皮层内抑制（SICI）生理学基础上我们所知道的和不知道的，以及我们如何填补未解问题的空白。

Short intracortical inhibition (SICI), measured using paired pulse TMS, is regularly employed to investigate motor cortex pathophysiology. Such studies have provided important supportive evidence of change in the balance between inhibition and excitation in many diseases. Although substantial information has been gathered to date about the neural networks and neurochemistry which give rise to SICI, many questions remain unanswered. In order to truly understand what SICI can tell us about motor cortex function and dysfunction, the existing evidence must be carefully considered and further investigations must be undertaken. In this webinar, Dr McMackin and Prof. Stagg will discuss what we do and do not know about the physiology underpinning SICI and how we can fill in the blanks for unanswered questions.

Hosts: Professor Charlotte Stagg (University of Oxford) and Dr Roisin McMackin (Trinity College Dublin)

主持人:牛津大学Charlotte Stagg教授和都柏林三一学院Roisin McMackin博士

时   间: May 26, 2021 02:00 PM BST (1 hr) 09:00 PM CST (北京时间）